Season 5 sees Piper deal with being a 圣女魔咒 One whilst being pregnant. She struggles between protecting her baby and accepting a 更多 passive role in fighting evil. After the birth and learning that she is the mother of a very important and powerful child, Piper must then face various demonic forces who intend to either kill 或者 capture her son. She also has problems in her marriage to Leo as they both feel the other doesn't appericate each other's responsibilites and needs.

Phoebe is finally able to let go of Cole emotionally, despite his re-appearance and constent tries to win her back. Her career as a columnist also begins to succeed as Phoebe becomes a local celebrity, while there she meets Jason Dean, the new editor, and begins a new romance with him.

Paige grows into her role as a 圣女魔咒 One and decides to give up her job to focus on a life of magic. She also learns to accept her whitelighter side as she is 给 her first charge who just happens to be her biological father Sam.