Majin Buu saga. Everybody got beaten in some form 或者 another. 悟空 was defeated in SSJ3, Gotenks beaten in SSJ3, 悟空 and Vegeta fusion were defeated, Gohan and his newfound 'Mystic' power was defeated, Vegeta was defeated in Majin form, Gohan was the first to be defeated 由 Buu in SSJ2 form. Basically, everybody got the snot kicked out of them in this.
Majin Buu...he ate Dabora king of the underworld. (You can't kill what can turn 你 into a cookie.) All the kai's feared him. He killed all the people on the Earth with a just one maneuver. Thats why he's at the end of Z. The worst threat always comes last in all Anima.